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Experimental Design

Experimental Design is an agent skill (a SKILL.md file) from K-Dense-AI/scientific-agent-skills. Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. It works with Claude Code, Codex, Cursor, Gemini CLI and GitHub Copilot and has 47,813 GitHub stars across a repository of 7 listed skills.

github.com/K-Dense-AI/scientific-agent-skills/skills/experimental-design (opens in a new tab)

Add this skill

Claude

Claude Code loads skills from ~/.claude/skills/ (all projects) or .claude/skills/ (one project):

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/experimental-design ~/.claude/skills/experimental-design   # personal, or .claude/skills in a project

In the Claude apps, zip the experimental-design folder and upload it under Customize > Skills > + > Upload a skill (code execution must be on).

ChatGPT / Codex

Codex reads skills from .agents/skills/ in a repo or ~/.agents/skills/ for every project:

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/experimental-design .agents/skills/experimental-design   # repo; ~/.agents/skills for all projects

Standalone skills also load in the ChatGPT desktop app.

Cursor

Cursor loads skills from .cursor/skills/ (or ~/.cursor/skills/) and also reads .claude/skills/:

git clone --depth 1 https://github.com/K-Dense-AI/scientific-agent-skills.git
cp -r scientific-agent-skills/skills/experimental-design .cursor/skills/experimental-design   # project; ~/.cursor/skills for all projects

Source (checked Oct 7, 2026): code.claude.com/docs/en/skills (opens in a new tab), support.claude.com/en/articles/12512180-using-skills-in-claude (opens in a new tab), learn.chatgpt.com/docs/build-skills (opens in a new tab), cursor.com/docs/context/skills (opens in a new tab)

What this skill does

Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. Use whenever someone is planning a study, asks how to assign subjects/samples to groups, mentions randomization, blocking, stratification, controls, factorial or fractional-factorial designs, design of experiments (DOE), screening many factors, response-surface optimization, crossover or repeated-measures or split-plot designs,…

When it triggers

  • Trigger even for informal phrasings like "how should I set up this experiment", "how do I avoid confounding", "what's the best way to test these 6 factors", or "assign these mice to conditions".
  • use statistical-power; for analyzing data already collected, use statistical-analysis.
  • "how should I set up this experiment"
  • "how do I avoid confounding"
  • "what's the best way to test these 6 factors"
  • "assign these mice to conditions"

More skills in K-Dense-AI/scientific-agent-skills

7 skills are listed from this repository.

FAQ

Experimental Design FAQ

Still curious? Email info@appsgit.com.

What is the Experimental Design skill?

Experimental Design is an agent skill (a SKILL.md file) from K-Dense-AI/scientific-agent-skills. Designs experiments and studies BEFORE data is collected — choosing a design, randomizing, blocking, and laying out treatment combinations so results are interpretable. It works with Claude Code, Codex, Cursor, Gemini CLI and GitHub Copilot and has 47,813 GitHub stars across a repository of 7 listed skills. Its SKILL.md lives at github.com/K-Dense-AI/scientific-agent-skills/skills/experimental-design.

How do I install the Experimental Design skill?

Copy the experimental-design folder (the one containing SKILL.md) into ~/.claude/skills/ for Claude Code, .agents/skills/ for Codex or .cursor/skills/ for Cursor. The agent picks it up automatically when a task matches its description.

Is the Experimental Design skill free?

Yes. The repository is open source under the MIT license.

Is Experimental Design maintained?

The repository's most recent commit was on Oct 5, 2026. Its latest release is v2.72.0. appsgit only lists skills from repositories with a commit in the last six months.