Best open source apps written in Python

1

Langflow

Visual framework for building and deploying AI agents and RAG workflows.

AI & LLM ToolsDocker

156k

AI-nativeStands out for a permissive MIT license. Langflow has 156,084 GitHub stars, uses the MIT license, ships a Docker image, is written in Python and had 2,758 commits in the last year.

2

Home AssistantFeatured

Home automation platform.

Home Automation & IoTDocker

92k

Stands out for the most commits in the last 12 months (21,554). Home Assistant has 91,788 GitHub stars, uses the Apache-2.0 license, ships a Docker image, is written in Python and had 21,554 commits in the last year; it replaces Nest / SmartThings and Google Home.

3

Dify.ai

Build, test and deploy LLM applications.

Source-availableLow-code & BackendDocker

160k

AI-nativeStands out for the most GitHub stars. Dify.ai has 159,780 GitHub stars, is source-available under the Dify Open Source License (modified Apache 2.0) (not an open-source license), ships a Docker image, is written in Python and had 6,840 commits in the last year.

4

Open-WebUI

User-friendly AI Interface, supports Ollama, OpenAI API.

Source-availableAI & LLM ToolsDocker

157k

AI-nativeStands out for AI features named in its own description. Open-WebUI has 157,004 GitHub stars, is source-available under the Open WebUI License (BSD-3-Clause plus branding clause) (not an open-source license), ships a Docker image, is written in Python and had 6,037 commits in the last year; it replaces ChatGPT and Lovable.

5

ComfyUI

Node-based interface and engine for diffusion image and video generation.

AI & LLM Tools

144k

AI-nativeStands out for the most recent release (v0.43.0, October 2026). ComfyUI has 143,662 GitHub stars, uses the GPL-3.0 license, is written in Python and had 2,109 commits in the last year.

6

Odoo

Free open source ERP system.

ERP & InventoryDocker

55k

Odoo has 55,380 GitHub stars, uses the LGPL-3.0 license, ships a Docker image, is written in Python and had 17,454 commits in the last year; it replaces NetSuite and SAP Business One.

7

Apache Airflow

Platform to programmatically author, schedule, and monitor workflows.

Automation & WorkflowsDocker

47k

Apache Airflow has 47,293 GitHub stars, uses the Apache-2.0 license, ships a Docker image, is written in Python and had 8,771 commits in the last year.

8

Paperless-ngx

Scan, index, and archive all of your paper documents with an improved interface (fork of Paperless).

Document ManagementDocker

47k

AI-nativePaperless-ngx has 47,176 GitHub stars, uses the GPL-3.0 license, ships a Docker image, is written in Python and had 1,786 commits in the last year.

9

Text Generation WebUI

Gradio web UI for running large language models locally.

AI & LLM ToolsDocker

48k

AI-nativeText Generation WebUI has 47,724 GitHub stars, uses the AGPL-3.0 license, ships a Docker image, is written in Python and had 699 commits in the last year.

10

Superset

Modern data exploration and visualization platform.

Analytics

75k

Superset has 75,336 GitHub stars, uses the Apache-2.0 license, is written in Python and had 6,135 commits in the last year; it replaces Metabase Cloud and Tableau.

11

ERPNext

ERP system to help you run your business.

ERP & InventoryDocker

41k

ERPNext has 40,687 GitHub stars, uses the GPL-3.0 license, ships a Docker image, is written in Python and had 10,424 commits in the last year; it replaces NetSuite and SAP Business One.

12

Frigate

Monitor your security cameras with locally processed AI.

Video SurveillanceDocker

37k

AI-nativeFrigate has 37,021 GitHub stars, uses the MIT license, ships a Docker image, is written in Python and had 1,620 commits in the last year; it replaces Ring.